Advertisement

Complex neuropathic pain states

      Abstract

      In this article we discuss complex neuropathic pain states: diabetic peripheral neuropathic pain (DPNP), phantom limb pain (PLP), central post-stroke pain, and complex regional pain syndrome (CRPS). Pain in these conditions can often be severe, significantly affect quality of life and be resistant to current treatment options. Multidisciplinary assessment and treatment are essential.

      Keywords

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Anaesthesia & Intensive Care Medicine
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Peltier A.
        • Goutman S.A.
        • Callaghan B.C.
        Painful diabetic neuropathy.
        BMJ. 2014; 348: g1799
        • Rajan R.S.
        • de Gray L.
        • George E.
        Painful diabetic neuropathy.
        Cont Educ Anaesth Crit Care Pain. 2014; 14 (Available at:): 230-235
        • Finnerup N.B.
        • Sindrup S.H.
        • Jensen T.S.
        The evidence for pharmacological treatment of neuropathic pain.
        Pain. 2010; 150 (Available at:): 573-581
        • National Institute for Health and Care Excellence
        Neuropathic pain in adults: pharmacological management in non-specialist settings. CG173.
        2020 (Available at:)
        • Jackson M.A.
        • Simpson K.H.
        Pain after amputation.
        Cont Educ Anaesth Crit Care Pain. 2004; 4 (Available at:): 20-23
        • Neil M.J.E.
        Pain after amputation.
        BJA Educ. 2016; 16 (Available at:): 107-112
        • Nikolajsen L.
        • Jensen T.S.
        Phantom limb pain.
        Br J Anaesth. 2001; 87: 107-116
        • Harrison R.A.
        • Field T.S.
        Post stroke pain: identification, assessment and therapy.
        Cerebrovasc Dis. 2015; 39 (Available at:): 190-201
        • Klit H.
        • Finnerup N.B.
        • Jensen T.S.
        Central post-stroke pain: clinical characteristics, pathophysiology, and management.
        Lancet Neurol. 2009; 8: 857-868
        • Liampas A.
        • Velidakis N.
        • Georgiou T.
        • et al.
        Prevalence and management challenges in central post-stroke neuropathic pain: a systematic review and meta-analysis.
        Adv Ther. 2020; 37: 3278-3291
        • Scuteri D.
        • Mantovani E.
        • Tamburin S.
        • et al.
        Opioids in post-stroke pain: a systematic review and meta-analysis.
        Front Pharmacol. 2020; 11: 587050
        • Royal College of Physicians
        Complex regional pain syndrome in adults (2nd edition). UK guidelines for diagnosis, referral and management in primary and secondary care.
        2018 (Available at:)
        • Ganty P.
        • Chawla R.
        Complex regional pain syndrome: recent updates.
        Cont Educ Anaesth Crit Care Pain. 2014; 14 (Available at:): 79-84
        • Edwards RR
        • Dworkin RH
        • Turk DC
        • et al.
        Patient phenotyping in clinical trials of chronic pain treatments: IMMPACT recommendations.
        Pain Rep. 2021; 6: E899