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The genesis of pain

  • Mike Hudspith
    Affiliations
    Mike Hudspith PhD FFPMRCA is a Consultant in Pain Medicine and Honorary Associate Professor (MED) UEA, Norfolk and Norwich University Hospital, Norwich, UK. Conflict of Interest: non declared
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      Abstract

      This article explores mechanisms that may generate pain as a multidimensional and embodied construct rather than a simple sensory state. Existing models of pain will be reviewed alongside dynamic functional imaging data and contemporary cognitive neuroscience principles, including Bayesian predictive processing, to provide a potential explanation of chronic pain states. The focus is upon an exploration of integrated cortico-limbic processing as opposed to peripheral and central sensitization.

      Keywords

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      Further reading

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