Anaesthesia & intensive care medicine
Volume 10, Issue 11 , Pages 538-540, November 2009

Adjuvant agents in regional anaesthesia

Sudhakar R Marri MBBS FCARCSI is a Clinical Research Fellow in Regional Anaesthesia at Ninewells Hospital and Medical School, Dundee, UK. Conflicts of interest: none declared

Matthew R Checketts FRCA is Consultant Anaesthetist at Ninewells Hospital and Medical School, UK. Conflicts of interest: none declared

Abstract 

Adjuvant drugs are agents that, when co-administered with local anaesthetic agents, may improve the speed of onset, the quality and/or duration of analgesia. A wide range of drugs have been assessed for both neuraxial and peripheral nerve blocks. Here, we review the adjuvants used in clinical practice in the UK and also briefly mention other drugs that have been used for neuraxial administration to provide perioperative analgesia.

Keywords: adjuvants, adrenaline, clonidine, ketamine, magnesium, neostigmine, opioids, sodium bicarbonate

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PII: S1472-0299(09)00206-9

doi:10.1016/j.mpaic.2009.08.001

Anaesthesia & intensive care medicine
Volume 10, Issue 11 , Pages 538-540, November 2009

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